Signal Transduction: How Rad53 Kinase Is Activated

نویسندگان

  • Achille Pellicioli
  • Marco Foiani
چکیده

Recent studies have elucidated the activation mechanism of the Rad53 checkpoint kinase and the role of Rad9-like adaptor proteins in mediating signal transduction from PIKK sensor kinases that detect DNA damage to the effector kinases that play a part in mending that damage.

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عنوان ژورنال:
  • Current Biology

دوره 15  شماره 

صفحات  -

تاریخ انتشار 2005